English
norskBlar i forfatter "Paulssen, Eyvind Jakob"
Viser treff 1-10 av 10
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The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-12)Background and aims: Previous research on H. pylori epidemiology has mostly focused on adult populations. We have aimed to study H. pylori prevalence in all age groups including children and adolescents and to identify potential routes of transmission. Methods: Subjects from all age groups (children 0–11 years, adolescents 12–17 years and adults ≥18 years of age), recruited from both an urban ... -
Clinical characterization of Helicobacter pylori infected patients 15 years after unsuccessful eradication
(Journal article; Tidsskriftartikkel, 2020-09-23)<i>Background and aims</i> - Patients that have failed therapy for Helicobacter pylori (H. pylori) infection are incompletely characterized. The aim of this study was to characterize a H. pylori treatment resistant cohort compared to the cohorts of newly diagnosed, earlier eradicated and non-infected.<p> <p><i>Material and methods</i> - Patients were selected from routine referrals to the Endoscopy ... -
Correlations between modest weight loss and leptin to adiponectin ratio, insulin and leptin resensitization in a small cohort of Norwegian individuals with obesity
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-02)Background - Weight loss is important to reduce the risk of metabolic complications in obese individuals, in whom dysregulated adipokines play a central role. This study aims to investigate whether dysregulated adipokines and postprandial triglycerides (TG) improve with a modest weight loss.<p> <p>Methods - Individuals with obesity (BMI ≥ 30 kg/m2) were recruited among patients at the University ... -
Future complications of chronic hepatitis C in a low-risk area: Projections from the hepatitis c study in Northern Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-16)<i>Background</i>: Hepatitis C (HCV) infection causes an asymptomatic chronic hepatitis in most affected individuals, which often remains undetected until cirrhosis and cirrhosis-related complications occur. Screening of high-risk subjects in Northern Norway has revealed a relatively low prevalence in the general population (0.24%). Despite this, late complications of HCV infection are increasing. ... -
Helicobacter pylori resistance to antibiotics before and after treatment: Incidence of eradication failure
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-20)Background <p>Increasing prevalence of antibiotic resistance especially to clarithromycin and metronidazole has been observed in Helicobacter pylori (H. pylori). <p>Aim <p>To characterize the antimicrobial resistance pattern of H. pylori before and after treatment in a cohort of patients accumulated over a period of 15 years after an unsuccessful eradication treatment had been given comparing ... -
Hepatic Steatosis detected by Hepatorenal Index in Ultrasonography as a Predictor of Insulin Resistance in Obese Subjects
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-20)BACKGROUND: The metabolic syndrome is a worldwide health issue, with non-alcoholic fatty liver disease (liver steatosis) being one of its features, particularly closely related to insulin resistance. This study aims to investigate whether quantification of hepatic steatosis by abdominal ultrasonography, using hepatorenal index, is a feasible tool for the prediction of insulin resistance, and thus ... -
Postprandial leptin and adiponectin in response to sugar and fat in obese and normal weight individuals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-11)<p><i>Purpose - </i>Adipokines produced by white adipose tissue are central in the development of lifestyle diseases. Individuals in industrialized countries spend a substantial part of life in the non-fasting, postprandial state, which is associated with increased oxidation and inflammation. The aim was to study postprandial adiponectin and leptin levels after an oral fat tolerance test (OFTT) and ... -
A rapid chemokine response of macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and the regulated on activation, normal T expressed and secreted chemokine is associated with a sustained virological response in the treatment of chronic hepatitis C
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)The role of chemokines in chronic hepatitis C virus (HCV) infection is not fully understood. The present study aimed to characterize the baseline serum concentrations and the initial β-chemokine response to treatment with interferon-α and ribavirin with respect to the final clinical outcome of virological response to treatment. Serum concentrations of alanine aminotransferase (ALT) and of the CC ... -
Screening for hepatitis C in a general adult population in a low-prevalence area: the Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-26)<i>Background - </i>Chronic hepatitis C virus (HCV) infection can progress to cirrhosis and end-stage liver disease in a substantial proportion of patients. The infection is frequently asymptomatic, leaving many infected individuals unaware of the diagnosis until complications occur. This advocates the screening of healthy individuals. The aim of this study was to estimate the prevalence of HCV ... -
Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-22)Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in many parts of the world but only a few cases have been diagnosed in Norway. To investigate the HEV exposure rate in a presumed low-risk area, we have conducted a population-based study of anti-HEV IgG seroprevalence in Northern Norway. A total of 1800 serum samples from 900 women and 900 men, age 40–79 years, were randomly selected ...
